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NONMEM hands-on workshop 21 to 25 May 2007, Aix-en-Provence, France

From: Olivier PETRICOUL <olivier>
Date: Wed, 6 Dec 2006 11:08:10 +0100

EMF Consulting is pleased to announce that the Workshop to be held on 21
to 25 May 2007 is open for registration.

Registrations are accepted on a first-come first-served basis.


This course is based on the NONMEM manuals, tutorials and varied
workshops run previously. Minimum theoretical lectures are given to
allow a naive NONMEM user to perform the exercises during the practical
hands-on sessions. The course is directed at pharmacokineticists,
clinical pharmacologists, and statisticians in pharmaceutical research.
We'll accept up to 10 trainees only.


English is the course language, EMF site is non-smoking and fully

Prerequisites: Basic understanding of PK, PKPD and clinical statistics.

Instructors: Eliane Fuseau, PhD, and Olivier Petricoul, PhD.



Lectures/ Discussion themes (~16 hours)

Day 1 Basic concepts of pharmacokinetic modelling, introduction to
population modelling, strategy for drug development (why and when), use
in market application (what).

Day 2 Modelling and precision, sources of variability, NMTRAN control
records, examples.

Day 3 NONMEM modelling strategy and documentation (protocol, analysis
plan, report), design, databases, constraints, diagnostics, model
selection, conditional estimation.

Day 4/5 PK, PKPD modelling (continuous and ordered categorical data),

Hands-on (~24 hours): starts on day 2, alternating with lectures.

Full problems are resolved and interpreted including PK and PKPD
modelling in individuals and in populations, exploring covariates, PKPD
simulations. PKPD exercises include blood pressure, QT data, and pain
severity scores. NONMEM is used on PCs with the interface Visual- NM,
for easy tables and graphs.


Registration, confirmation and fees: Download/print/fax the registration
form from our web site (

Confirmation of your registration will be sent with an invoice. Fees
are EUR2400 if paid before the workshop, or EUR2460 after the workshop
(French academics), preferably by SWIFT bank transfer at the following

Credit Du Nord Aix-Sextius, 16 Cours Sextius, BP 86 Aix en Provence
cedex 1 BIC NORDFRPP IBAN FR76 3007 6022 3227 9276 0020 094 Bank Code
30076 Branch Code 2232 Account No 27927600200 cle 94


Registration fees includes coffee breaks and lunch every day, one diner
on Tuesday.


Eliane Fuseau, PhD


EMF Consulting

425 rue Rene Descartes

BP 02

13545 Aix-en-Provence cedex 4

tel +33 442 908 102

fax +33 442 908 101

mobile +33 622 040 516



Received on Wed Dec 06 2006 - 05:08:10 EST

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