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Re: Bayesian estimation example

From: Nitin Mehrotra <nitin_utmem>
Date: Wed, 11 Apr 2007 10:38:15 -0700 (PDT)

Hi Tausif,
   
  You are probably talking about two different things. You can obviously get the emperical bayesian individual esimates using NONMEM. But performing a Bayesian Estimation is a different approach which utlizes prior information and current data to generate posterior distribution of the parameter estimates.
   
  There is an excellent pharmacometerics learning tool on www.accp1.org which provides theory and examples on population analysis and might be very helpful to you.
   
  Hope this helps
   
  Regards
   
  Nitin
  


Tausif Ahmed <tausif.ahmed
      Dear Group members,
   
  I have recently started using NONMEM for population analysis.
  I need you help in understanding Bayesian estimation using NONMEM.
  Can any body provide me a sample control stream along with data file (Excel or csv format) and also explain the output.
  I use Visual NM to run NONMEM version V.
   
  Thanking you in anticipation.
   
  Regards
  Tausif Ahmed Ph.D.
  Metabolism and Pharmacokinetics Department
  Ranbaxy Research Lab
  India
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    Nitin Mehrotra, Ph.D
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  Department of Pharmaceutical Sciences
  University of Tennessee Health Science Center
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  nmehrotr
   



       
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Received on Wed Apr 11 2007 - 13:38:15 EDT

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