NONMEM Users Network Archive

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Re: batches with different half-life - linear PK

From: Alison Boeckmann <alisonboeckmann>
Date: Sat, 21 Apr 2007 17:53:01 UT

Sorry, here are the remarks.

On Sat, 21 Apr 2007 10:51:39 -0700, "Alison Boeckmann"
<alisonboeckmann
> Please see attached remarks and files.
>
> ----------
> On Thu, 19 Apr 2007 14:54:11 +0000 (GMT), nonmem
> > Hello NONMEM Users,
> >
> > Sometimes the same subjects receive the same drug from different batches.
> > Potentially, half-life can be different accross batches. Theoretically,
> > it is easy to model if PKis linear because NONMEM superimposes
> > single-dose processes to obtain predicted concentrations for multiple
> > doses. Does enyone know how to implement it in NONMEM? Are there any
> > classes or publications which can help?
> >
> > Thanks!
> > Pavel
> --
> Alison Boeckmann
> alisonboeckmann
>
--
  Alison Boeckmann
  alisonboeckmann


  • application/octet-stream attachment: remarks
Received on Sat Apr 21 2007 - 13:53:01 EDT

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