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2007 San Francisco Fisher/Shafer NONMEM Workshop

From: Steven Shafer <steven.shafer>
Date: Mon, 30 Apr 2007 18:25:05 -0700

Fisher/Shafer NONMEM Course in San Francisco



Dates: Wednesday, June 27, 2007 through Sunday, July 1, 2007


Course Organizers:

Dennis Fisher, MD, The "P <" Company

Steven Shafer, MD, Stanford University


Web Site:


The fifth Fisher/Shafer NONMEM Workshop will be held Wednesday, June 27,
2007 through Sunday, July 1, 2007 at the Nikko Hotel in San Francisco.


The Fisher/Shafer NONMEM Workshop covers NONMEM (version 6), data =
model building, and model diagnostics. The workshop includes an =
set of example problems ranging from simple didactic examples to =
basic concepts to complex examples from the instructors' own =
Registrants are provided with a comprehensive set of graphical tools
programmed in the R statistical language to create high-quality =
and analysis plots. Registrants are also given Windows scripts to =
NONMEM analyses and provide audit trails.


The distinguishing characteristic of this workshop is that each =
brings his or her laptop computer. A copy of NONMEM, the GNU Fortran
Compiler, the Windows and UNIX scripts, the full set of examples, and R =
all provided to the users on a USB drive (flash drive) on Thursday =
(Wednesday afternoon for those in the Introduction to NONMEM workshop or =
R workshop - see below). The entire course is run from the USB drive,
leaving no footprint on the registrant's computer. NONMEM is removed at =
end of the course, but the other software is in the public domain and =
may be
kept after the course. The registrant follows along with the =
testing examples on his or her laptop as the instructor works through =


Although a wide variety of NONMEM examples are provided for training, at
least half of the course participants bring real data from their work to =
course. Typically these are data sets that require complex models =
to the participants, or are data that have been refractory to =
modeling approaches. The course provides an opportunity for participants =
review their data with the course instructors. Typically users leave the
course with the tools required to model their data and with insight into =
reason the data were difficult to model.


The workshop runs from Thursday morning until Sunday noon. Each day =
6 hours of instruction, ending at 3 pm. From 3 pm until 5 pm, =
work on either the example problems, or on a data set of the =
choosing (frequently a difficult problem from work).


The course is intended for individuals at the intermediate level. Those
without substantial NONMEM experience are urged to sign up for the
beginner's workshop described below. This should be adequate preparation =
allow the novice to follow the main workshop.


Because NONMEM is such a flexible tool, experienced NONMEM users have =
the NONMEM Workshop valuable. In part, this is because the course
instructors bring their unique perspectives to the application of NONMEM =
data analysis. It is also because of the breadth of examples provided.
Experienced users will find the introduction on Wednesday afternoon too
basic, but they may find the R workshop on Wednesday morning to be =


This course will be based on NONMEM 6 recently released from Globomax.


Wednesday Half-Day Courses

Introduction to R

Wednesday, 8 am - noon

This course, given Wednesday morning, covers the R statistical =
language. Within the regular workshop, all participants will be =
to the use of R to create diagnostic graphics for NONMEM. However, =
time will be devoted to understanding the code used in these graphics. =
course provides a more extensive introduction to the use of R (and the
closely related language S-Plus). R is a remarkable tool for data
management, graphics, and statistics. This session will focus on the use =
R to read data, assemble a NONMEM dataset, perform basic statistics, and
generate graphics.


Introduction to NONMEM

Wednesday 1 pm - 5 pm

For those with little or no prior experience with NONMEM, we will =
provide a
day session on the Wednesday afternoon before the course to prepare =
for the Intermediate course described above. Registrants will be taught =
basics of NONMEM: 1) constructing a control stream, 2) constructing a =
file, and 3) running NONMEM.


The course description, schedule, and application for the workshop be =
at <> .




Steven L. Shafer, MD

Professor, Department of Anesthesia, Stanford University

Adjunct Professor, Biopharmaceutical Sciences, UCSF

Editor-in-Chief, Anesthesia & Analgesia


Received on Mon Apr 30 2007 - 21:25:05 EDT

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