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Interesting job position within Discovery PKPD

From: Gabrielsson, Johan <Johan.Gabrielsson>
Date: Wed, 20 Aug 2008 15:10:05 +0200

Advanced PKPD scientist in Drug Discovery
(Astrazeneca R&D, Mölndal, Sweden)
We are looking for an experienced (> 3 years post PhD experience) =
Pharmacokineticist/PKPD scientist to our PKPD section with a key =
responsibility to develop and apply PKPD strategies, study designs and =
analyses within the Drug discovery phase within one of our most =
prioritised Disease area segments, Diabetes and Obesity.
The arena
As one of the world´s leading Pharmaceutical companies, our business =
is focused on turning good ideas into innovative, effective medicines =
that make a real difference in important areas of healthcare.
AstraZeneca is one of the world's leading pharmaceutical companies, with =
a broad range of medicines designed to fight disease in important areas =
of healthcare. Backed by strong science and wide-ranging commercial =
skills, we are committed to sustainable development of our business and =
the delivery of a flow of new medicines that make a difference in the =
lives of patients and create value for our shareholders and wider =
society. We are active in over 100 countries with growing presence in =
important emerging markets; corporate office in London UK; major R&D =
sites in Sweden, the UK and the US.
The position is placed within the PKPD section of the Dx DMPK Department =
within the Research area CVGI (Cardiovascular and Gastrintestinal =
research) in Mölndal, Astrazeneca, R&D Sweden. The position offers a =
great opportunity to apply your pharmacokinetic and PKPD skills by =
implementing our PKPD based Drug Discovery strategy and applying state =
of the art PKPD study design and analyses within one of our most =
prioritised Disease areas. You will work in an advanced Drug Discovery =
setting together with other highly competent PKPD and Pharmacology =
The role
One of your main responsibilities will be to represent the Discovery =
DMPK Department in a cross functional Disease area Team and be =
responsible for developing PKPD strategies for all new projects emerging =
within a segment of the Disease area.
By applying state of the art PKPD principles in study design and =
analyses, you will actively contribute to
· Target validation studies for emerging targets
· Develop PKPD strategies and establish a PKPD understanding for new =
targets and chemical classes in relation to critical Milestone =
· Generate preclinical PKPD data for potential Candidate drugs =
including translational aspects and assure a good transfer of knowledge =
into the Development organisation
In addition you will be critical in the development and spreading of =
the PKPD competence and the general PKPD strategy within the Research =
The role does not include responsibility for staff and you report =
directly to the Head of the PKPD section.
Minimum experience/requirements
· A PhD (or equivalent experience) in pharmacokinetics/PKPD with >3 =
years of industry or academic post PhD experience
· Excellent understanding of drug disposition and pharmacological =
· Demonstrated hands-on Modeling experience from e.g. WinNonlin
· Proven leadership capabilities
· Excellent English - written and verbal communications skills
· A collaborative, open minded and team oriented spirit
Preferred experience/requirements
· Experience from the application of PKPD in Drug Discovery is a clear =
· Experience from Population modeling (e.g NONMEM) is of additional =
More information
For more information, please contact Dr Ulf Bredberg, Head of PKPD =
Phone: +46 (0) 705 86 13 98.

To apply: You apply via our homepage at
Click on careers then Job opportunities and then locate the position. =
Then follow the instructions.
Closing date: August 31
Received on Wed Aug 20 2008 - 09:10:05 EDT

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