NONMEM Users Network Archive

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RE: ETA on ALAG1

From: Xiao, Alan <Alan.Xiao>
Date: Fri, 12 Dec 2008 17:04:58 -0500

Objective function could be negative.
ALAG1 variability could be correlating with Ka variability depending on =
what your data look like.
 
Alan

-----Original Message-----
From: owner-nmusers
[mailto:owner-nmusers
ayyappa.5.chaturvedula
Sent: Friday, December 12, 2008 4:00 PM
To: nmusers
Subject: [NMusers] ETA on ALAG1



Dear All,

It is an old topic, but definetely not completely resolved. Can anybody =
provide tips on estimating variability on ALAG1 in a 2 comp, oral =
absorption model (I am using NONMEM V). I am getting an error message =
OBJFUN is negative. I have searched in usernet archive but could not =
solve the problem. I appreciate your help.

Regards,
Ayyappa Chaturvedula
GlaxoSmithKline
1500 Littleton Road,
Parsippany, NJ 07054
Ph:9738892200


Received on Fri Dec 12 2008 - 17:04:58 EST

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