NONMEM Users Network Archive

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calculation of individual weight with duplicate essays

From: kai wu <kaiwu77>
Date: Tue, 15 Jul 2008 08:31:51 -0700 (PDT)

Dear all,   I am using L2 item and between essay EPS to deal with exis=
tance of duplicate essays from some PK samples in the dataset.   I am =
wondering how to calculate the individual weight for output IWRES.   Th=
anks in advance.  $ERROR IPRE=F  BEV=ERR(1) IF (GRG.EQ.1) =
BEV=ERR(2) Y=F*(1+ERR(3)+BEV)+ERR(4) $SIGMA BLOCK(1) 0.01 ;Betwe=
en Essay ERR(1) $SIGMA BLOCK(1) SAME $SIGMA .04 4       =
   ;ERR(4) initialized at (LOQ/2)^2  Regards/Kai
Received on Tue Jul 15 2008 - 11:31:51 EDT

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