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RE: PPC

From: andreas lindauer <lindauer>
Date: Thu, 31 Jul 2008 13:27:14 +0200

Hello NMUSERS,

 

Let me just add one more thought on the bootstrap discussion. Sometimes =
when
doing a bootstrap it happens that the runs terminate because of =
parameter
estimates near to the boundary (e.g. values for OMEGA close to 0). When =
this
happens in a considerable number of runs, lets say in 10% of the runs, =
how
would you then calculate the CI for that parameter? Because the =
bootstrap
parameter distribution derived from all runs - irrespective of their
termination status - would then be bimodal with one mode close to the
boundary.

 

Best regards, Andreas.

 

____________________________

 

Andreas Lindauer

 

University of Bonn

Department of Clinical Pharmacy

An der Immenburg 4

D-53121 Bonn

 

phone:+49 228 73 5781

fax: +49 228 73 9757

 


Received on Thu Jul 31 2008 - 07:27:14 EDT

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