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Use of ADDL and II

From: Batul Parta <batulparta>
Date: Wed, 12 Nov 2008 07:36:13 -0800 (PST)

Dear All,

I am modeling a repeated dosing study. Subjects were given twice daily dose=
s for 8 weeks and a number of samples were taken on the last day of dosing.=
 There were also sparse samples taken at weeks 2, 4, and 6. I want to use A=
DDL and II for the dosing scheme. Can I lump all doses into one line or do =
I have to stop the dosing record prior to each sample and re-start again? I=
n other words, will the following file structure work:

ID TIME AMT   ADDL  II   DV
1    0      10      112    12   0
1    143   0         0       0   12=
4
1    287   0         0       0   13=
1
.
.
.

Or do I have to use the following:

ID TIME AMT   ADDL  II   DV

1    0      10      14      12   0

1    143   0         0       0   12=
4
1    144   10      14      12   0

1    287   0         0       0   13=
1
.
.
.

Thank you in advance.

BP


Received on Wed Nov 12 2008 - 10:36:13 EST

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