NONMEM Users Network Archive

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Re: Why population PK approach is good for pooling data compared to Classical statistical analysis?

From: Nick Holford <n.holford>
Date: Fri, 17 Oct 2008 07:38:06 +1300


As far as I know any 'classical statistical analysis' that one can do
using regression can be done with NONMEM. It is also possible to do
hypothesis testing on means (t-test, ANOVA), logistic regression and
survival analysis.
What kinds of 'classical statistical analysis' do you want to do that
you cannot do with NONMEM?


> Dear Group,
> Could anybody explain or direct me to some literature why population
> PK approach allows us to pool data from different studies but no
> classical statistical analysis?
> Regards,
> Ayyappa Chaturvedula
> GlaxoSmithKline
> 1500 Littleton Road,
> Parsippany, NJ 07054
> Ph:9738892200

Nick Holford, Dept Pharmacology & Clinical Pharmacology
University of Auckland, 85 Park Rd, Private Bag 92019, Auckland, New Zealand
Received on Thu Oct 16 2008 - 14:38:06 EDT

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