NONMEM Users Network Archive

Hosted by Cognigen

Re: Why population PK approach is good for pooling data compared to Classical statistical analysis?

From: Nick Holford <n.holford>
Date: Fri, 17 Oct 2008 07:38:06 +1300

Ayyappa,

As far as I know any 'classical statistical analysis' that one can do
using regression can be done with NONMEM. It is also possible to do
hypothesis testing on means (t-test, ANOVA), logistic regression and
survival analysis.
What kinds of 'classical statistical analysis' do you want to do that
you cannot do with NONMEM?

Nick


ayyappa.5.chaturvedula
>
> Dear Group,
>
> Could anybody explain or direct me to some literature why population
> PK approach allows us to pool data from different studies but no
> classical statistical analysis?
>
> Regards,
> Ayyappa Chaturvedula
> GlaxoSmithKline
> 1500 Littleton Road,
> Parsippany, NJ 07054
> Ph:9738892200

--
Nick Holford, Dept Pharmacology & Clinical Pharmacology
University of Auckland, 85 Park Rd, Private Bag 92019, Auckland, New Zealand
n.holford
http://www.fmhs.auckland.ac.nz/sms/pharmacology/holford
Received on Thu Oct 16 2008 - 14:38:06 EDT

The NONMEM Users Network is maintained by ICON plc. Requests to subscribe to the network should be sent to: nmusers-request@iconplc.com.

Once subscribed, you may contribute to the discussion by emailing: nmusers@globomaxnm.com.