NONMEM Users Network Archive

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Career Opportunity

From: Jay Chapman <jchapman>
Date: Tue, 7 Apr 2009 16:30:57 -0400

Job Description: Position Description and Responsibilities: As a member of
the Modeling and Simulation group, you will lead the design and conduct
population exposure response modeling analysis to investigate relationships
between drug exposure and safety, efficacy data for investigational new
drugs preparing clinical exposure response reports for regulatory agencies,
including the U.S. Food and drug Administration. Perform model based
exposure response simulations to optimize

the selection of dosing regimes that maximize efficacy and minimize adverse
reactions. Characterize exposure response relationships in special patient
population such as patients with renal or hepatic impairment using
population exposure response approaches to ensure the proper labeling of
dosing regimen, safety and efficacy. Develop novel modeling and simulation
methods by integrating knowledge and techniques from multiple fields,
including biology, clinical pharmacology,

Education Requirements:

Doctor of Philosophy degree in Pharmaceutical Sciences along with Three -
Five years of experience in Strategic

Exposure Response Modeling and Simulation, PKPD, SPlus, NONMEM or a related

Experience Requirements:

Strong oral and written communication skills necessary to formally present
and report information internally and externally is required. The ability to
work in a dynamic team oriented environment is essential.



Jay Chapman

Hughes and Associates




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Received on Tue Apr 07 2009 - 16:30:57 EDT

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