NONMEM Users Network Archive

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the puzzle in the covariance

From: yhb5442387
Date: Sun, 13 Dec 2009 14:43:43 +0800 (CST)

Dear professor:

THE off diagnoal:

Sometimes we make the OMEGA syntax as follows:$omega 0.1 0.1,but $omega blokc (2) 0.1 0.01 0.1 at another occasion.As we know,the only difference is whether the off diagonal estimate be used.So is there any specila condition about the existence of the W21,or some another W square like that?

Thank you !!!

Received on Sun Dec 13 2009 - 01:43:43 EST

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