NONMEM Users Network Archive

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RE: NONMEM 7 Update

From: Eleveld, DJ <d.j.eleveld>
Date: Thu, 2 Jul 2009 23:32:23 +0200

Dear all:

There is no debate at all that investment in NONMEM should have a healthy return. I just dont understand how encryption is supposed to help.

NONMEM 6 was not encrypted, what problems resulted from this? Did anything actually happen to the NONMEM 6 source code which must be avoided with NONMEM 7?

The thinking "we must encrypt our souce code so nobody steals our IP" may be suitable for consumer goods where copyright violations are rampant and visibility is very low. But the small, highly specalized and very visible community of PK-PD analysis is a very different thing. My impression is that everyone takes thier NONMEM licences very seriously and I dont see any reason why this would change with NONMEM 7.

There are usually upsides and downsides to these kinds of choices and a balance must be struck. I can think of a number of downsides to encryption but no real upsides. I was hoping to hear from others what the upside was. Just "protecting our IP" is, in my opinion, not a real reason becasue this does not actually generate any revenue.

Douglas Eleveld


-----Oorspronkelijk bericht-----
Van: Ludden, Thomas [mailto:Thomas.Ludden
Verzonden: do 2-7-2009 15:15
Aan: Eleveld, DJ; nmusers
CC: Krohn, Anthony
Onderwerp: RE: [NMusers] NONMEM 7 Update
 
Dear All:

        Icon Development Solutions has invested in the further
development of NONMEM. By mutual agreement with the University of
California at San Francisco, NONMEM 7 is intellectual property belonging
to IDS. However, IDS will continue to pay royalties to UCSF.
         
        The business plan under which NONMEM 7 was developed calls for
the protection of the I.P. involved. In addition, NONMEM 7 contains
several updated routines developed and owned by IMSL (Visual Numerics
Inc.). Our agreement with IMSL stipulates that we will not distribute
their source code. The installer will compile the software but will not
allow the unencrypted source code to remain on the users computer. The
licensing agreement will also stipulate that any attempt to access the
source code will be a violation of the agreement.
         
        Some source code will be left unencrypted for various reasons,
one being the need for users to change certain values in SIZES and
perhaps other resource routines.
        

        
        Tom

        Thomas M. Ludden Ph.D.
        Vice-President, Pharmacometrics R&D
        ICON Development Solutions

        Tel: + 1 410 696 3040
        Mob: + 1 410 258 2411
        Fax: + 1 410 480 0776
        Email: thomas.ludden

        Web: www.icondevsolutions.com

        
<http://emailsignature/stationary/Icon_Development_Solutions.gif>

         

         


________________________________

From: Eleveld, DJ [mailto:d.j.eleveld
Sent: Thursday, July 02, 2009 6:11 AM
To: Ludden, Thomas; nmusers
Subject: RE: [NMusers] NONMEM 7 Update


Can anyone explain what advantages encryted source code might have?
 
For me at least, the NONMEM source code is already functionally
encrypted because of my poor understanding of Fortran. But it is
unclear to me what problem encryted source code actually solves. Can
anyone enlighten me?
 
Douglas Eleveld

________________________________

From: owner-nmusers xnm.com on behalf of Ludden, Thomas
Sent: Wed 01/07/2009 9:21 PM
To: nmusers
Subject: [NMusers] NONMEM 7 Update


Dear All:
 
This is just a brief update regarding the availability of NONMEM 7. We
had hoped to begin distribution of this new version at this time.
However, there are some final code changes to be made followed by
thorough testing. We hope to be able to begin distribution in early
August.
 
Please be certain that the contact information that we have on file for
your license(s) is up to date. This is the person to whom NONMEM 7 will
be sent . Please send any updates regarding the correct contact person
to IDSSOFTWARE ARE
 
Please note that NONMEM 7 will have a licensing system. More details
will be provided as we approach the release date.
 
Our experience with distributing binary code to the beta testers was
very mixed. Some testers had no problems; others had considerable
difficulty with achieving a successful installation. We are now
considering the distribution of NONMEM 7, for the most part, as
encrypted source code. An installation program will be included. The
SIZES file and several other resource files will be left unencrypted so
that the user can make desired changes prior to compilation as was
possible with previous versions. This change in our method of
distribution will require that a revised licensing agreement be
executed.
 
Regards,
 
Bob Bauer
Vice-President, Pharmacometrics
 
Alison Boeckmann
Consultant
 
Bill Bachman
Director, Pharmacometrics R&D
 
Tom Ludden
Vice-President, Pharmacometrics R&D

ICON Development Solutions

Tel: + 1 410 696 3040
Mob: + 1 410 258 2411
Fax: + 1 410 480 0776
Email: thomas.ludden

Web: www.icondevsolutions.com



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________________________________

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ICON plc made the following annotations.
------------------------------------------------------------------------------
This e-mail transmission may contain confidential or legally privileged information
that is intended only for the individual or entity named in the e-mail address. If you
are not the intended recipient, you are hereby notified that any disclosure, copying,
distribution, or reliance upon the contents of this e-mail is strictly prohibited. If
you have received this e-mail transmission in error, please reply to the sender, so that
ICON plc can arrange for proper delivery, and then please delete the message.
Thank You,
ICON plc
South County Business Park
Leopardstown
Dublin 18
Ireland
Registered number: 145835




De inhoud van dit bericht is vertrouwelijk en alleen bestemd voor de geadresseerde(n). Anderen dan de geadresseerde(n) mogen geen gebruik maken van dit bericht, het niet openbaar maken of op enige wijze verspreiden of vermenigvuldigen. Het UMCG kan niet aansprakelijk gesteld worden voor een incomplete aankomst of vertraging van dit verzonden bericht.

The contents of this message are confidential and only intended for the eyes of the addressee(s). Others than the addressee(s) are not allowed to use this message, to make it public or to distribute or multiply this message in any way. The UMCG cannot be held responsible for incomplete reception or delay of this transferred message.
Received on Thu Jul 02 2009 - 17:32:23 EDT

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