NONMEM Users Network Archive

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RE: RE: NONMEM 7 Update

From: Eleveld, DJ <d.j.eleveld>
Date: Fri, 3 Jul 2009 22:40:19 +0200

Serge, I am afraid I dont understand what you are getting at.

Are you trying to say that so few people in the world understand the NONMEM code
and so noone is likely to complain that they cant understand the encrypted code?

Or are you trying to say that so few people in the world understand the NONMEM code
and so encryption is rather pointless since it changes almost nothing?


-----Original Message-----
From: owner-nmusers m on behalf of Serge Guzy
Sent: Fri 7/3/2009 9:56 AM
To: Thierry.Buclin
Subject: Re: [NMusers] RE: NONMEM 7 Update
I do have only one simple question. How many people took advantage from the fact Nonmem was distributed as open source? If we are talking about a very small percentage, is this discussion worthwhile? How many people except bob bauer and may be somebody else I am not aware of are able to follow and understand the cuirrent nonmem code?


From: owner-nmusers
To: Ludden, Thomas ; nmusers
Sent: Thu Jul 02 23:46:09 2009
Subject: [NMusers] RE: NONMEM 7 Update




Didn't ICON consider that indeed, this decision might stimulate the divergence of an open-source clade of NONMEM, somewhat like R stemmed out of S-plus? If a small academic group starts to work in that direction, it would certainly be quickly joined by many.


Thierry Buclin

Univ. Hospital, Lausanne


De : owner-nmusers s
Envoyé : jeudi, 2. juillet 2009 15:15
À : Eleveld, DJ; nmusers
Cc : Krohn, Anthony
Objet : RE: [NMusers] NONMEM 7 Update


Dear All:

        Icon Development Solutions has invested in the further development of NONMEM. By mutual agreement with the University of California at San Francisco, NONMEM 7 is intellectual property belonging to IDS. However, IDS will continue to pay royalties to UCSF.


        The business plan under which NONMEM 7 was developed calls for the protection of the I.P. involved. In addition, NONMEM 7 contains several updated routines developed and owned by IMSL (Visual Numerics Inc.). Our agreement with IMSL stipulates that we will not distribute their source code. The installer will compile the software but will not allow the unencrypted source code to remain on the users computer. The licensing agreement will also stipulate that any attempt to access the source code will be a violation of the agreement.


        Some source code will be left unencrypted for various reasons, one being the need for users to change certain values in SIZES and perhaps other resource routines.


        Thomas M. Ludden Ph.D.
        Vice-President, Pharmacometrics R&D
        ICON Development Solutions

        Tel: + 1 410 696 3040
        Mob: + 1 410 258 2411
        Fax: + 1 410 480 0776
        Email: thomas.ludden


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Received on Fri Jul 03 2009 - 16:40:19 EDT

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