NONMEM Users Network Archive

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RE: NONMEM 7 Update

From: Samer Mouksassi <smouksassi>
Date: Fri, 3 Jul 2009 15:14:32 -0700

Dear NMusers,

How many of NMusers had to look at the sources routine during their
daily PK/PD modeling? And Why ?

In the past I had to look at the source code to decipher vague errors
that I could not understand until I went to the fortran routine and see
at which circumstances this error is issued.

Other instances where I looked at the source code is when:
I needed to see which commons have the correlation matrix/ the R/ RINV,
S matrices...to be able to output these with more precision. (Happily,
NMVII will allow more control on the outputs precision).

Also I wanted to look at some undocumented features to be able to use
them:
e.g: the PHI function was previously available but undocumented.
Also to see more details about the numerical method used to approximate
the phi function...

In the nonmem help many entries ask the interested user to study the NM
code to understand and see how can use these advanced features.

With the encryption of the source code, can we expect more extensive and
complete documentation and flexible user controls?

Bests,

Samer Mouksassi
Received on Fri Jul 03 2009 - 18:14:32 EDT

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