NONMEM Users Network Archive

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Re: Parameter Shrinkage

From: IOrtega
Date: Tue, 7 Jul 2009 08:40:43 +0200

Maybe, this presentation could provide you some information.

Importance of Shrinkage in Empirical Bayes Estimates for Diagnostics and
Estimation: Problems and Solutions
Radojka M. Savic and Mats O. Karlsson

"Hudachek,Susan" <Susan.Hudachek
Enviado por: owner-nmusers
06/07/2009 21:46


[NMusers] Parameter Shrinkage

Greetings All! I am revising a pop PK paper and one of the reviewers would
like to see parameter shrinkage reported. Does anyone know how to compute
this? And, what is considered "low" verses "high" shrinkage? Thanks so
much in advance for any help you can offer!
Susan Hudachek, M.S., Ph.D.
Animal Cancer Center
Veterinary Teaching Hospital
Colorado State University
300 West Drake Road
Fort Collins, CO 80523-1620
PHONE: (970) 219-7599
FAX: (970) 297-1254
EMAIL: Susan.Hudachek

Received on Tue Jul 07 2009 - 02:40:43 EDT

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