NONMEM Users Network Archive

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RE: calculation of AUC

From: Martin Bergstrand <martin.bergstrand>
Date: Fri, 20 Mar 2009 13:44:47 +0100

Dear Ethan,


You need to provide more information on how you plan to calculate AUC
otherwise the question can't be answered. It is of course possible to
calculate the AUC without any influence of the sampling frequency. You
should be able to find examples of how to do this in the NMusers archive.
See for example the answer from Mats Karlsson in this thread


Kind regards,


Martin Bergstrand, MSc, PhD student


Department of Pharmaceutical Biosciences,
Uppsala University


P.O. Box 591

SE-751 24 Uppsala





Work: +46 18 471 4639

Mobile: +46 709 994 396

Fax: +46 18 471 4003



From: owner-nmusers
Behalf Of Ethan Wu
Sent: den 20 mars 2009 13:05
To: nmusers
Subject: [NMusers] calculation of AUC


Hi all, to calculate AUC of one of the compartments using ADVAN6, if it is a
fixed time interval, will the AUC be influenced by the frequncy of sampling
of the dataset within this interval or not?



Received on Fri Mar 20 2009 - 08:44:47 EDT

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