NONMEM Users Network Archive

Hosted by Cognigen

Re: time-dependent residual error models

From: Nick Holford <n.holford>
Date: Thu, 24 Sep 2009 17:45:39 +1200

Hi,

If Phylinda reads this I'd be interested to hear why she choose to use a
plain vanilla first-order absorption model and a fancy time-dependent
residual error model rather than trying to model a fancy absorption
process with a plain vanilla residual error model?

Nick

Joseph Standing wrote:
>
> Xiang,
>
>
>
> There is a rather elegant time-dependent residual error model
> described by Phylinda Chan et al in:
>
> BJCP, 2008;65(S1):76-85.
>
>
>
> BW,
>
> Joe
>

--
Nick Holford, Professor Clinical Pharmacology
Dept Pharmacology & Clinical Pharmacology
University of Auckland, 85 Park Rd, Private Bag 92019, Auckland, New Zealand
n.holford
mobile: +64 21 46 23 53
http://www.fmhs.auckland.ac.nz/sms/pharmacology/holford
Received on Thu Sep 24 2009 - 01:45:39 EDT

The NONMEM Users Network is maintained by ICON plc. Requests to subscribe to the network should be sent to: nmusers-request@iconplc.com.

Once subscribed, you may contribute to the discussion by emailing: nmusers@globomaxnm.com.