NONMEM Users Network Archive

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Re: time-dependent residual error models

From: Nick Holford <n.holford>
Date: Thu, 24 Sep 2009 17:45:39 +1200


If Phylinda reads this I'd be interested to hear why she choose to use a
plain vanilla first-order absorption model and a fancy time-dependent
residual error model rather than trying to model a fancy absorption
process with a plain vanilla residual error model?


Joseph Standing wrote:
> Xiang,
> There is a rather elegant time-dependent residual error model
> described by Phylinda Chan et al in:
> BJCP, 2008;65(S1):76-85.
> BW,
> Joe

Nick Holford, Professor Clinical Pharmacology
Dept Pharmacology & Clinical Pharmacology
University of Auckland, 85 Park Rd, Private Bag 92019, Auckland, New Zealand
mobile: +64 21 46 23 53
Received on Thu Sep 24 2009 - 01:45:39 EDT

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