NONMEM Users Network Archive

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simluation Tmax Cmax AUC

From: yhb5442387
Date: Wed, 21 Apr 2010 23:17:42 +0800 (CST)

Dear Nmuser:

   I would like to do a data simulation .The distributions of the drug population pharmaockinetics were assumed to be normal.But the profile that I have got is Tmax, Cmax,and AUC(the means and variances are already known),instead of Ka,CL,and V. What the $PK modification should I have to do in the model where the advan2 has been taken in the $subroutine.

F=1.

 

Any suggestion would be appreciated.

 

Yours,ye hong bo





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Received on Wed Apr 21 2010 - 11:17:42 EDT

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