NONMEM Users Network Archive

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transit model after IV dose?

From: Ann Rigby-Jones <ann.rigby-jones>
Date: Wed, 20 Jan 2010 17:14:29 +0000

Dear All

I am interested in trying a transit model in an attempt to better describe =
early drug concentrations following intravenous injection (1 minute and 10 =
minute infusions) of a sedative-hypnotic drug. I found some examples of tr=
ansit model control streams following oral administration but I wondered if=
 someone might be able to help me with an example following IV dosing, as I=
'm currently unsure of the implementation in NONMEM?

I'd be very grateful for any advice you could offer :)

With thanks and all best wishes

Ann Rigby-Jones PhD MRSC
Research Fellow in Pharmacokinetics & Pharmacodynamics

Peninsula College of Medicine & Dentistry
England, UK


Received on Wed Jan 20 2010 - 12:14:29 EST

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