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RE: missing table file

From: Jing Nie <hollidayy>
Date: Thu, 21 Jan 2010 10:12:51 -0500


Dear All,

Thank you for all the inputs. I tried to change .fit to .tab, but no tabl=
e file still. After Switching from FOCI to FO method with POSTHOC, I get =
the table output . Also, If I just remove the $cov step but keep using FO=
CI, the table file is produced.

Jing


 

 

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> Date: Thu, 21 Jan 2010 00:12:08 -0500
> From: LGibiansky
> To: n.holford
> CC: Matt.Fidler
xnm.com
> Subject: Re: [NMusers] missing table file
>
> Sometimes table file is not printed if/when covariance step fail. Try
> remove $COV statement; it could help to get $TABLE output. Also,
> sometimes FO method is completed successfully but POSTHOC fails; then
> table file is not produced either. But the error message seems to point
> to $COV step.
> Thanks
> Leonid
>
> --------------------------------------
> Leonid Gibiansky, Ph.D.
> President, QuantPharm LLC
> web: www.quantpharm.com
> e-mail: LGibiansky at quantpharm.com
> tel: (301) 767 5566
>
>
>
>
> Nick Holford wrote:
> > Matt,
> >
> > WFN would not affect whether NONMEM decides to output a table file.
> >
> > I have never seen the error message RMATX- 1. Some errors will stop
> > NONMEM from producing a table file.
> >
> > Jing,
> >
> > There is no such thing as a MASM listing file. I suspect you are talkin=
g
> > about the raw NONMEM output file with the extension .lst.
> >
> > Please look at the .lst file in the run folder. You should find more
> > information there about the error and perhaps some indication of why it=
 
> > happened.
> >
> > Nick
> >
> > Fidler,Matt,FORT WORTH,R&D wrote:
> >> Jing,
> >>
> >> It appears that you ran this using Wings for NONMEM. Have you tried
> >> running using nmfe6 or nmfe7?
> >>
> >> Matt.
> >>
> >> ----------------------------------------------------------------------=
--
> >> *From:* Jing Nie [mailto:hollidayy
> >> *Sent:* Wednesday, January 20, 2010 4:00 PM
> >> *To:* Fidler,Matt,FORT WORTH,R&D
> >> *Subject:* RE: [NMusers] missing table file
> >>
> >> Matt,
> >>
> >> The NONMEM output I got as following:
> >>
> >> THETA: KOUT SMAX SC50
> >> ETA: BSVKOUT BSV_SMAX BSV_SC50
> >> ERR:
> >>
> >> 1drA_amt.lst 257.613 eval=430 sig=3.3 sub=53 obs=53 CCIL=
=YNYN
> >> NVI1.2 PV1.0
> >> THETA = 0.0538 0.337 346
> >> ETASD = 0 1.01489 22.2711
> >> ERRSD = 5.46809
> >>
> >> MINIMIZATION SUCCESSFUL
> >>
> >> P VAL.: 0.68E+00 0.11E-01 0.52E+00
> >> ERROR RMATX- 1
> >>
> >> the run is able to generate .smy, .smr,.ctl and MASM listing file =
but
> >> no table.
> >>
> >> Jing
> >>
> >>
> >>
> >> This e-mail and any files transmitted with it, are intended solely f=
or
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> >> have received this e-mail in error, please reply to this message and=
 
> >> let the sender know.
> >>
> >>
> >>
> >>
> >> ----------------------------------------------------------------------=
--
> >> From: Matt.Fidler
> >> To: hollidayy
> >> Date: Wed, 20 Jan 2010 15:48:59 -0600
> >> Subject: RE: [NMusers] missing table file
> >>
> >> Jing,
> >>
> >> Please post all of your nonmem output.
> >>
> >> Matt.
> >>
> >> ----------------------------------------------------------------------=
--
> >> *From:* owner-nmusers
> >> [mailto:owner-nmusers
> >> *Sent:* Wednesday, January 20, 2010 1:01 PM
> >> *To:* nmusers
> >> *Subject:* [NMusers] missing table file
> >>
> >> Dear NMusers,
> >>
> >> I'm trying to run a control stream using NONMEM6. Minimization was
> >> successful but there is one error message RMATX -1. I get the output
> >> file with obj values and other estimates but I don't have the table
> >> file. My table record is posted below:
> >>
> >> $TABLE ID TIME IPRE NOPRINT ONEHEADER FILE=1.fit
> >>
> >> I searched the archive and add the carriage return to the $table
> >> record and still got no tables.
> >> Is it has something to do with this error message? Any suggestion is
> >> appreciated.
> >>
> >>
> >> Jing
> >>
> >>
> >>
> >>
> >>
> >>
> >>
> >>
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> >> let the sender know.
> >>
> >>
> >>
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> >> Thank you.
> >
> > --
> > Nick Holford, Professor Clinical Pharmacology
> > Dept Pharmacology & Clinical Pharmacology
> > University of Auckland,85 Park Rd,Private Bag 92019,Auckland,Ne=
w Zealand
> > tel:+64(9)923-6730 fax:+64(9)373-7090 mobile:+64(21)46 23 53
> > email: n.holford
> > http://www.fmhs.auckland.ac.nz/sms/pharmacology/holford
> >
                                               
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Received on Thu Jan 21 2010 - 10:12:51 EST

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