NONMEM Users Network Archive

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simulation problem or bug

From: Leonid Gibiansky <LGibiansky>
Date: Mon, 23 May 2011 16:26:42 -0400

Dear All,
I am trying to run simulations starting from the msf file (nm 7.1).
I've done it multiple times for the current project without any
problems. BUT for one specific problem, I see a very strange behavior:
The simulation script runs just fine with SUBPROBLEMS=0 option, but
fails with any other value (including 1) with the following error:

0MULTIPLE SUB_PROBLEMS IS INCOMPATIBLE WITH OTHER INFORMATION
  IN THE CONTROL STREAM AND INPUT MSF

I am not sure whether it is important but the original run completed
with 134 (rounding error) estimation error and successful covariance
step (with UNCONDITIONAL option)

Any ideas of what is the problem?

Thanks!
Leonid

--
--------------------------------------
Leonid Gibiansky, Ph.D.
President, QuantPharm LLC
web: www.quantpharm.com
e-mail: LGibiansky at quantpharm.com
tel: (301) 767 5566


Received on Mon May 23 2011 - 16:26:42 EDT

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