NONMEM Users Network Archive

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Re: [NMusers] Simulo: a new service for drug trial simulation

From: Leonid Gibiansky <lgibiansky_at_quantpharm.com>
Date: Tue, 23 Jun 2015 10:13:35 -0400

Actually, nonmem can be used to simulate the response-based dose
adaptation without iteratively rerunning your model, with single
simulation (using $ABB COMRES functionality to pass simulated response
to the dose-adjustment algorithm code), although it is indeed cumbersome

Leonid

--------------------------------------
Leonid Gibiansky, Ph.D.
President, QuantPharm LLC
web: www.quantpharm.com
e-mail: LGibiansky at quantpharm.com
tel: (301) 767 5566



On 6/23/2015 4:48 AM, Faelens, Ruben (Belgium) wrote:
> Dear NONMEM users,
>
> We all know how difficult it is to simulate full drug trials using
> NONMEM. It is often necessary to generate the full dosing scheme(s)
> beforehand, and response-based dose adaptation requires iteratively
> rerunning your model until you have the results you are happy with.
>
> At SGS Exprimo, we have been working for 4 years to develop a new
> software that makes drug trial simulation much more straight-forward.
> The software has been developed in collaboration with Roche and has been
> used internally within SGS Exprimo for the last 2 years. We are now
> presenting it to the public as a new consultancy service. You may have
> seen us in Crete at PAGE 2015.
>
> We invite you to visit our website www.simulo.eu <http://www.simulo.eu>
> or contact us directly to request an on-site demo or web conference, or
> to ask any questions you may have.
>
> We look forward to hearing from you.
>
> Kind regards,
>
> Ruben Faelens for SGS Exprimo
>
> *Ruben Faelens, MSc*
> *Life Science Services - Exprimo*
> IT Scientist
>
> Phone:
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> +32 494 06 72 59
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> _ruben.faelens_at_sgs.com <mailto:ruben.faelens_at_sgs.com>_
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> www.exprimo.com <http://www.exprimo.com/>
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> Information in this email and any attachments is confidential and
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Received on Tue Jun 23 2015 - 10:13:35 EDT

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