NONMEM Users Network Archive

Hosted by Cognigen

[NMusers] postdoctoral position - pharmacokinetics of antibiotics in specific populations of patients

From: Françoise Van Bambeke <>
Date: Sat, 30 May 2015 18:34:52 +0200

The Cellular and Molecular Pharmacology Research group
(Louvain Drug Research Institute, Université
catholique de Louvain, Brussels, Belgium)
has an open position for a postdoctoral fellow (M/F)
(3 years).

Research topic:

Pharmacokinetics of antibiotics in specific populations of patients

Background and aim of the project:
PK/PD is a modern way of optimizing antibiotic
usage (efficacy and safety). Important
variations in pharmacokinetics are observed in
specific patients’ populations (patients with
renal or hepatic insufficiency, obese patients,
pediatric patients for example), so that standard
doses may not be optimal. The project aims at
studying pharmacokinetics of specific
beta-lactams in pediatric patients in order to
define an optimized dose, based on PK/PD
concepts. The study will be completed by a
microbiological study on the activity of these
beta-lactams against contemporary clinical
isolates, including in in vitro pharmacodynamics models.

Skills: strong experience in pharmacokinetics
(including population pharmacokinetics and Monte
Carlo Simulations) and HPLC, if possible, also experience in microbiology.

How to apply (deadline: June 10, 2015):
* Send to Prof F. Van Bambeke (
o a motivation letter
o a curriculum vitae (including a publication list),
o 2 recommendation letters, and the name and
email address of 2 reference persons
* Specific conditions to apply:
o PhD degree (in biomedical or pharmaceutical
sciences, or any other relevant discipline)
o no previous stay > 12 months in Belgium during the last 3 years
Date of beginning work : > October 2015

Description of the laboratory:
The laboratory is located in the outskirts of
Brussels, Belgium, with easy access by public
transportation. The team counts 3 permanent
researchers, 4 post-doctoral fellows, 8 PhD
students, 4 technicians and 5-10 undergraduate
students. Language spoken include French and English.
The activities of the laboratory and the
publications of the team are available on the website (

Françoise Van Bambeke, PharmD, PhD
Pharmacologie Cellulaire et Moléculaire
(Cellular and Molecular Pharmacology)
Université Catholique de Louvain
(Catholic University of Louvain)
avenue E. Mounier 73 bte B1.73.05
B-1200 Bruxelles (Belgium)



tel.: 32-2-764.73.78
secr. 32-2-764.73.70

Received on Sat May 30 2015 - 12:34:52 EDT

The NONMEM Users Network is maintained by ICON plc. Requests to subscribe to the network should be sent to: Once subscribed, you may contribute to the discussion by emailing: