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[NMusers] FWD: Pharmacometrician Position at MedImmune California

From: Das, Indrajit <Indrajit.Das_at_iconplc.com>
Date: Mon, 16 Nov 2015 22:11:46 +0000

Please contact Bing Wang, wangbi_at_medimmune.com<mailto:wangbi_at_medimmune.com=
>, for further details about the following position. Thanks,

My company shares my passion for helping to improve human health around the=
 world.





"This is My MedImmune"



Those who join MedImmune feel a sense of ownership about their future. They=
 thrive with a recognized leader in the biotechnology industry and the whol=
ly-owned subsidiary of AstraZeneca plc. Here, you will join passionate prof=
essionals who advance science, technology and medicine to develop products =
designed to help people live better lives. You will excel in an environment=
 characterized by respect, integrity and growth opportunities... that encou=
rages both individual contribution and collaborative entrepreneurial thinki=
ng. Our products and/or product candidates are designed to address areas of=
 need in infection, oncology, respiratory disease and inflammation, cardiov=
ascular/metabolic disease and neuroscience. Explore a MedImmune career as w=
e strive to better more lives, more often, around the world.



Title

Senior Pharmacometrician/Principal Pharmacometrician






Location

CA, Mountain View

Job Description

This position can be filled at either the Senior Pharmacometrician or Princ=
ipal Pharmacometrician level depending upon experience.

This is a strategic and scientific role within Clinical Pharmacology & DMPK=
 (CPD), which provides nonclinical and clinical PK/PD, pharmacometrics and =
bioanalytical support for biotherapeutics projects at all R&D stages from d=
iscovery research to BLA registration and commercialization.

The pharmacometrician will conduct advanced population modeling and stochas=
tic clinical trial simulations for late-stage biotherapeutics projects. In =
collaboration with clinical pharmacokineticists, statisticians and physicia=
ns, the pharmacometrician will work as a partner in cross-functional projec=
t teams providing sophisticated M&S support for clinical dose recommendatio=
n, optimal trial design, rational develop
This is a strategic and scientific role within Clinical Pharmacology & DMPK=
 (CPD), which provides nonclinical and clinical PK/PD, pharmacometrics and =
bioanalytical support for biotherapeutics projects at all R&D stages from d=
iscovery research to BLA registration and commercialization.

The pharmacometrician will conduct advanced population modeling and stochas=
tic clinical trial simulations for late-stage biotherapeutics projects. In =
collaboration with clinical pharmacokineticists, statisticians and physicia=
ns, the pharmacometrician will work as a partner in cross-functional projec=
t teams providing sophisticated M&S support for clinical dose recommendatio=
n, optimal trial design, rational ment decision making, and regulatory fili=
ngs.

~BSP

Position Requirements

Education:
Senior Pharmacometrician
A doctorate degree with demonstrated expertise in pharmacometrics and stron=
g quantitative skills is required and 2- 5 years of relevant industry exper=
ience

Principal Pharmacometrician
A doctorate degree with demonstrated expertise in pharmacometrics and stron=
g quantitative skills is required and 5- 8 years of experience for .

Prior experience in regulatory filings is highly desirable for Sr Pharmacom=
etrician and required for Principal Pharmacometrician.

Position:
Proven track record of extensive experience in population modeling and simu=
lations using NONMEM. Familiarity with statistical software package Splus, =
R or SAS.
Good communication and scientific writing skills, and ability to independen=
tly work in a matrix environment.
Leverage M&S expertise to address key clinical development questions. Provi=
de strategic input into clinical development plans. Responsible for the M&S=
 components in late-stage trial designs and data interpretation.
Use innovative quantitative approaches to integrate knowledge of PK, PD, ef=
ficacy, safety, patient demographics, and pathophysiological factors to fac=
ilitate product development decision making. Perform mechanistic PK-PD and =
disease modeling to establish dose-exposure-response relationship.
Contribute to the regulatory submission packages, and participate in regula=
tory meetings as appropriate. Interact with clinical pharmacokineticists an=
d monitor outsourced modeling activities to ensure quality of the work and =
timely delivery of the results.
Utilize published external data to enhance the knowledge of diseases and tr=
eatments, and to facilitate the development of internal drug candidates.
Actively promote MedImmune as a biopharmaceutical leader in the utilization=
 of quantitative model-based drug development approach. Support MedImmune p=
ublication strategy. Present and report data in approved external conferenc=
es and scientific/medical journals.

*LI-MEDI





Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled/Sex=
ual Orientation

Additional Notes

Req ID

10190



Bing Wang, PhD
Clinical Pharmacology & DMPK
MedImmune <br /><br /> ICON plc made the following annotations. -----=
-------------------------------------------------------------------------=

information that is intended only for the individual or entity named in the=
 e-mail address. If you are not the intended recipient, you are hereby no=
tified that any disclosure, copying, distribution, or reliance upon the con=
tents of this e-mail is strictly prohibited. If you have received this e-=
mail transmission in error, please reply to the sender, so that ICON plc ca=
n arrange for proper delivery, and then please delete the message. Tha=
nk You, ICON plc South County Business Park Leopardstown Dublin =
18 Ireland Registered number: 145835




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Received on Mon Nov 16 2015 - 17:11:46 EST

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