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RE: [NMusers] $Error log transformed

From: <R.terHeine_at_radboudumc.nl>
Date: Fri, 16 Dec 2016 10:23:53 +0000

Hi Katrin,
You'll have to take the natural logarithm of your DVs

I would change your error block to:

$ERROR
IPRED=LOG(F+1E-16) ; Protection against LOG(0) in case of dosing events =
etc
Y=IPRED+ERR(1) ; FOR PROPORTIAL ERROR

Cheers!
Rob


Van: owner-nmusers_at_globomaxnm.com [mailto:owner-nmusers_at_globomaxnm.com] Nam=
ens Katrin Volz
Verzonden: vrijdag 16 december 2016 10:35
Aan: nmusers_at_globomaxnm.com
Onderwerp: [NMusers] $Error log transformed

Dear All,

I would like to model my data log transformed.
So far, I already found some suggestions for this problem here but none of =
them worked in my case - probably I did sth. wrong.

I would be very happy if someone could help me with changing my error model=
, which I assume has to be changed.
(I also assume that the dataset has to be changed from DV to LOG(DV)?)

So, here is the code I used so far (not log transformed):

$ERROR
IPRED = F ;IPRED drug i=
n the central compartment
IF (CMT.EQ.5) IPRED = A(5) ;IPRED second drug in 5th compar=
tment

DEL=0
IF (IPRED.EQ.0) DEL=0.0001
W = F
IRES = DV - IPRED
IWRES = IRES /(W + DEL)

Y = IPRED + IPRED * EPS(1) ; error drug =
in the central compartment
IF (CMT.EQ.5) Y = IPRED + IPRED * EPS(2) ; error second drug in 5th c=
ompartment

It would be great to get some help.
Thanks!
Katrin





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Received on Fri Dec 16 2016 - 05:23:53 EST

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