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[NMusers] Error message since switching to NONMEM 7.3

From: Mai, Tu [MED] <tmai1_at_medicine.bsd.uchicago.edu>
Date: Mon, 4 Jan 2016 22:06:08 +0000

Dear nmusers,

I am using NONMEM 7.3 for a simple PD modeling analysis. I was able to run =
this file in NONMEM 7.2 but after the switching, I got this error message. =
NONMEM asked for the *tabdn101 file (my mod file name is dn101.mod). Can yo=
u please help? Thank you very much!


0ITERATION NO.: 15 OBJECTIVE VALUE: -2830.13313592389 NO. OF F=
UNC.
EVALS.: 6
CUMULATIVE NO. OF FUNC. EVALS.: 114
NPARAMETR: 9.6232E-04 9.4126E-03 1.9896E+00 1.3094E+00 6.2668E-02
PARAMETER: -1.7824E+00 2.4309E+00 4.4397E-01 -3.9158E-01 -1.3366E-01
GRADIENT: 8.6164E-02 -4.8788E-02 8.0264E-02 -8.6181E-02 5.0536E-02
Elapsed estimation time in seconds: 2.61
Elapsed covariance time in seconds: 1.75
        1 file(s) copied.
        1 file(s) copied.
        1 file(s) copied.
*tabdn101
The system cannot find the file specified.
        0 file(s) copied.
Pirana: All runs finished / submitted.
Done

I include here my mod file as well. Thank you

$PROB RUN# finalnm
$INPUT C ID TIME PSA PSAbase DV
$DATA dn101final2.csv IGNORE=C

$PRED
KL = THETA(1)*EXP(ETA(1))
KD = THETA(2)*EXP(ETA(2))

IPRED = EXP( KL * TIME ) + EXP( - KD * TIME ) - 1

Y = IPRED + ERR(1)

 DEL=0
IF (F.EQ.0) DEL=1
W=Y
IRES=DV-IPRED
IWRES=IRES/(W+DEL)

$THETA
(0,0.006,0.1) ; KL
(0,0.001,0.1) ; KD

$OMEGA
1 ;[P]
3.5 ;[P]

$SIGMA
0.1

$EST PRINT=10 MAXEVAL=9999 METHOD=1 INTER
$COV
$TABLE ID TIME IPRED WRES CWRES KL KD ETA1 ETA2 ONEHEADER NOPRINT FILE= f=
ulldata.tab
$TABLE ID ETA1 ETA2 CWRES ONEHEADER NOPRINT FILE=PATAB_1
$TABLE ID CWRES ONEHEADER NOPRINT FILE=COTAB_1
$TABLE ID TIME IPRED IWRES CWRES ONEHEADER NOPRINT FILE=SDTAB_1
$TABLE ID ONEHEADER NOPRINT FILE=CATAB_1

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Thank you
University of Chicago Medicine and Biological Sciences
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Received on Mon Jan 04 2016 - 17:06:08 EST

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