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Associate Director position at Neklar Therapeutics

From: Gordi, Toufigh <TGordi>
Date: Mon, 11 Jul 2016 17:25:35 +0000

Associate Director, Pharmacometrics
Position Summary
Nektar Therapeutics is seeking an experienced PK/PD expert to join the comp=
any at the Associate Director (AD) level. The position is in the pharmacome=
tric group, a part of the clinical pharmacology department and the new AD w=
ill work closely with other modelers and non-modelers to advance drug candi=
dates from preclinical to late clinical phases.
Help apply quantitative analysis methods and PK/PD modeling techniques in d=
eveloping candidate drug products from pre-IND through Phase III. Plan and =
execute the PK/PD modeling and simulation (M&S) activities in the design an=
d analysis of in vivo and in vitro studies working with a multidisciplinary=
 team. Conduct and collaborate with others on the principles and theories =
of quantitative evaluation of new products and maintenance of existing phar=
macokinetics and drug metabolism product lines through the application of s=
tate-of-the-art knowledge in PK/PD analysis. In collaboration with other t=
eam members make decisions impacting PK/PD goals and the success and releva=
nce of individual preclinical and clinical studies. Contribute to the desi=
gn and preparation of preclinical and clinical pharmacokinetics development=
 strategies and study protocols, performing and supervising pharmacokinetic=
 and pharmacodynamic analyses, and preparation of clinical study reports an=
d integrated summary documents. Provide feedback and direction for regulat=
ory submissions preparation and review support for new or existing products=
. Work closely with clinical operations, biostatistics, data management, r=
esearch, drug metabolism and therapeutics areas. Take over and maintain Ne=
ktar's storage of pharmacometric files and archive system.

What we offer: Nektar Therapeutics is in the early stages of implementing a=
 model-based drug development paradigm (MBDD) throughout the organization. =
The current position offers an exciting opportunity to be a contributing pa=
rt of the company's efforts in such implementation. We offer a highly colla=
borative and scientific environment and the opportunity to shape the future=
 of the company's path toward a more effective and science-based drug devel=
opment process.
The right person for this position has a PhD in pharmaceutical sciences and=
 PK/PD analysis and 10 years of industry experience. Expert knowledge of sc=
ientific principles of pharmacometrics and relevant software are essential.=
 Independent analysis and problem solving and the ability to implement the =
solutions using available tools are critical. The pharmacometric group is w=
ell integrated in the clinical pharmacology department and the AD is expect=
ed to contribute to a highly collaborative team. Scientific curiosity, outg=
oing personality, and willingness to help other team members with complex p=
roblems by offering science-based solutions, while learning new insights ar=
e highly desirable.

Toufigh Gordi, PhD, MBA
Senior Director of Pharmacometrics
Nektar Therapeutics
Tel.: 415-482-5306
Email: tgordi

Received on Mon Jul 11 2016 - 13:25:35 EDT

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