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[NMusers] Opening Position in Pharmacometrics, Servier, France

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Date: Thu, 7 Dec 2017 08:58:03 +0000

Opening Position in Pharmacometrics, Servier, France

Servier is an international pharmaceutical company governed by a non-profit=
 Foundation and headquartered in France.
With a strong international presence in 148 countries and a turnover of 4 b=
illion euros in 2016, we employ over 21,000 people worldwide.
Being completely independent, we reinvest 25% of turnover (excluding generi=
cs) in Research and Development and use all our profits in growth.
We are specialized and driven by our constant search for innovation in five=
 major research areas: cardiovascular diseases, cancers, diabetes, immuno-i=
nflammatory diseases and neurodegenerative diseases, as well as by our acti=
vities in high-quality generic drugs.
Currently, we have 23 drug candidates including 19 new molecular entities a=
t various stages of clinical development.
Our priorities are pathologies with high medical needs within our areas of =

Company Strategy & 2020 Goals
- Increase Research output : launch on the market one new molecular en=
tity every 3 years
- Achieve sales of 5 billion Euros
- Become a key player in oncology and reinforce the group's presence i=
n its historical therapeutic areas, especially cardiology.


The Centre of Excellence in Pharmacokinetics (CentEx PK) at Servier has ope=
ning positions for pharmacometricians in early phase PKPD (from Research to=
 phase 1 included), late phase PKPD (from phase 2 to registration), and in =
Physiological Based PK modelling (PBPK).
The candidates will be full-time dedicated to modelling activities to suppo=
rt pre-clinical and clinical development programmes. The candidates will ha=
ve strong relationships with other modellers in pharmacometrics (i.e. PBPK,=
 early phase and late phase popPK & PKPD modelling) and stakeholders within=
 and outside Servier (i.e. clinicians, pharmacologists, partners, CRO etc..=

The candidates will be responsible for:

· Defining the modelling strategy in collaboration with other pro=
ject members.

· Study design, data analysis plan, modelling & simulation, and t=
o communicate outcomes and give recommendations.

· Presenting modelling activities to internal/external experts in=

Candidates at senior level will also participate to:

· The improvement of modelling tools and methodological developme=
nt within the CentEx PK.

· Junior mentoring in pharmacometrics.

· The promotion of modelling activities within the Servier group.

Skills and Experience
You hold a PhD in a relevant area (PKPD/PBPK modeling, Biological Sciences,=
 Pharmacology, Statistics, Engineering, Pharmaceutical Sciences or other re=
lated discipline). You are fluent in English, both orally and written, and =
have good communication and presentation skills. The pharmacometrics group =
at Servier is located in France (Suresnes near Paris and Orléans). Workin=
g knowledge of French is not a requirement.
Several positions are open and we are looking for junior (with a first expe=
rience in applying Pharmacometrics in a professional environment) and senio=
r (with at least 5 years in a pharmaceutical company) scientists.
The positions in early phase PKPD and late phase PK/PD require a good knowl=
edge of modelling software (such as NONMEM or MONOLIX), and visualisation t=
ools (R, SAS).
The position in PBPK requires a good knowledge of PBPK software such as Sim=
CYP, GastroPlus or PKSim.

You have an analytical mind-set and a strong desire to further develop and =
apply modelling and simulation in drug development. You appreciate working =
in teams of scientists with different backgrounds and the opportunity of ex=
panding your network at an international level.
We offer an exciting opportunity for developing your professional skills an=
d for working with projects with many challenges and with support from a ra=
nge of highly skilled professionals.

For further information, please contact Marylore Chenel: marylore.chenel_at_se=

Marylore Chenel, PharmD PhD
Director of Clinical PK and PMx
Institut de Recherches Internationales Servier
50, rue Carnot, 92284 Suresnes Cedex, France
Phone: 00 33 1 55 72 38 56, Cell: 00 33 6 70 07 25 36

Received on Thu Dec 07 2017 - 03:58:03 EST

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