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M&S Summer Internship at Allergan

From: Luu_Ken <Ken.Luu>
Date: Mon, 13 Mar 2017 16:52:22 +0000

The Pharmacometrics/Modeling and Simulation (M&S) discipline within the Tra=
nslational and Clinical Pharmacology group at Allergan (Irvine, CA) is seek=
ing a summer intern for 2017. The incumbent will be working under the direc=
tion of an M&S scientist on data mining and data visualization with intent =
to develop a predictive ocular PBPK model to support research and translati=
onal science. The incumbent will be interacting closely with ADME scientist=
s and clinical pharmacologists to mine and collect internal and literature =
ocular PK data. The ideal candidate is preferred to be enrolling in a docto=
ral or master's program in one of the following disciplines: pharmacokineti=
cs, pharmacometrics, pharmaceutical sciences, biostatistics, data programmi=
ng or mathematics. Experience in the following areas, though not strictly r=
equired, is a plus: PBPK modelling, NONMEM, WinNonlin, SAS and/or R program=
ming. This is an opportunity for the intern to gain exposure to modelling =
and simulation within a pharmaceutical industry setting.

The employee must conduct their work activities in compliance with all rele=
vant laws, regulations, and regulatory guidelines as well as all Allergan p=
olicies and procedures.

Main Areas of Responsibilities
* Mining Allergan internal, and if necessary, literature ocular PK =
data in various preclinical species and potentially human
* Organize and program datasets to make them amendable for modeling
* Perform data visualization for hypothesis testing
* Perform data analysis using WinNonlin to calculate various PK par=
ameters in ocular tissues
* Create centralized repository folders to store these data
* Depending on the incumbent's skillset, develop a predictive PBPK =
model with the intent to provide recommendations for animal use reduction a=
nd cost savings
* Present data to group and symposium at the end of the program
* In addition, the incumbent is the key contact for Pharmacometrics=
, and ADME scientists.
* The incumbent may attend project team and group meetings to gain =
industry/project-support experience
* In addition, the incumbent is the key contact for Clinical Pharma=

* B.S. or equivalent degree is required
* The ideal candidate is preferred to be enrolled in a doctoral or ma=
ster's program in one of the following disciplines: pharmacokinetics, pharm=
acometrics, pharmaceutical sciences, biostatistics, data programming or mat=
* Must be enrolled as a full-time student at an accredited universit=
y and in good academic standing.
* Must have valid U.S. work authorization without the need for spons=
orship by the company.
* Must be able to work full-time for 10-12 weeks for the duration of=
 the internship.
* No relocation, transportation, or housing assistance will be provi=

Contact Kenneth Luu directly or visit this link for more detail and apply:

Kenneth T. Luu, PhD
Director, Pharmacometrics
Non-Clinical and Translational Sciences
2525 Dupont Drive (RD2-2087), Irvine, CA 92612
* 714.246.2803 | 6 714.246.6510 | * ken.luu

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Received on Mon Mar 13 2017 - 12:52:22 EDT

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