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Re: [NMusers] current sigma

From: 樋坂章博 <hisaka_at_public.email.ne.jp>
Date: Thu, 8 Nov 2018 19:10:46 +0900

Thanks, Robert

I confirmed the values are available.

Akihiro


On 2018/11/08 5:10, Bauer, Robert wrote:
> Try the following examples, according to your need, in $PRED or $PK:
>
> SIGVAL11=SIGMA(1,1)
> OVAL22=OMEGA(2,2)
>
> IF(NEWIND.eq.0) WRITE(*,*) SIGVAL11,OVAL22
> ...
> $TABLE SIGVAL11 OVAL22
>
>
> Robert J. Bauer, Ph.D.
> Senior Director
> Pharmacometrics R&D
> ICON Early Phase
> 820 W. Diamond Avenue
> Suite 100
> Gaithersburg, MD 20878
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>
> -----Original Message-----
> From: owner-nmusers_at_globomaxnm.com
> <mailto:owner-nmusers_at_globomaxnm.com>
> [mailto:owner-nmusers_at_globomaxnm.com] On Behalf Of ryota-j_at_chiba-u.jp
> <mailto:ryota-j_at_chiba-u.jp>
> Sent: Sunday, November 04, 2018 7:03 PM
> To: nmusers_at_globomaxnm.com <mailto:nmusers_at_globomaxnm.com>
> Subject: [NMusers] current sigma
>
> Hello,
>
> I would like to know how to know current sigma values in a customized PRED
> routine. In noncom.for file, it is documented that initial and final
> theta,
> omega and sigma values are set in ROCM6, and current omega values are
> set in
> ROCM22. However, I cannot find current sigma values.
>
> We developed a new program which can restore numerous time-course data by
> expanding the analysis of nonlinear mixed effect model. Detail of our
> analysis, named SReFT, is described in recent Clin Pharm Ther
> (PMID:29951994). Currently, SReFT is implemented in my own program, Napp,
> but I am considering its implementation in NONMEM. For the
> implementation of
> SReFT, it is necessary to know current sigma value in the PRED routine.
>
> Akihiro Hisaka,
> Chiba University, Japan.
> email: hisaka_at_public.email.ne.jp <mailto:hisaka_at_public.email.ne.jp>
>
>
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Received on Thu Nov 08 2018 - 05:10:46 EST

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