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Quantitative Clinical Pharmacology Position at GSK

From: Chao Chen <chao.c.chen>
Date: Tue, 30 Jul 2019 12:52:45 +0000

We have an exciting opportunity at GlaxoSmithKline (GSK) for a highly motiv=
ated Quantitative Clinical Pharmacologist to join our London team as part o=
f the global department of Clinical Pharmacology Modelling & Simulation. Th=
is is an excellent role to use quantitative clinical pharmacology to accele=
rate the delivery of new medicines to patients by enhancing drug program ef=
ficiency and business decision quality. The work directly supports our miss=
ion to help our patients do more, feel better and live longer.
Responsibilities will include:
1. Plan, execute and report translational drug-disease modelling, exposure-=
response analysis, simulation-based trial design and population clinical ph=
* 2. Contribute to clinical program design, trial protocols, analysis=
 plans, study reports and regulatory submissions
* 3. Apply innovative techniques such as longitudinal exposure-respon=
se analysis, model-based meta-analysis and item-response analysis to improv=
e data use and trial efficiency
* 4. Present strategy and discuss outcome of model-based approaches v=
ia interactions with internal governance boards and regulatory agencies
* 5. Promote model-informed drug discovery and development through ex=
ternal collaboration, journal publication and conference presentation
Qualification requirements:
1. A doctorate relevant to Quantitative Clinical Pharmacology, and experien=
ce in using modelling/simulation to solve practical problems in industry or=
2. Proven skills in pharmacokinetic-pharmacodynamic and longitudinal diseas=
e modelling; and verifiable proficiency in pharmacometric tools NONMEM, Mon=
olix, R or SAS
3. Strong drive and learning agility to build knowledge on a drug-disease s=
ystem, symptom progression, standard of care, and trial design and endpoint=
4. Demonstrated aptitude for productive collaboration in a multi-discipline=
 team, using effective communication and taking personal accountability for=
 timely delivery of results
5. Clear evidence of ability to make sound judgement in complex situations =
and adapt to changing business needs by prioritising multiple tasks
The job level will depend on the skills and achievements of the successful =
candidate. At GSK, we develop therapies of various modalities for a broad r=
ange of indications. As a member of a global department with diverse expert=
ise, you will enjoy a highly supportive environment for scientific innovati=
on, business impact and professional growth. This position is open for appl=
ication till Wednesday 5th August 2019. Interested persons are encouraged t=
o apply online here<
Chao Chen
Clinical Pharmacology Modelling & Simulation
GlaxoSmithKline R&D

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This e-mail was sent by GlaxoSmithKline Services Unlimited
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member of the GlaxoSmithKline group of companies. The
registered address of GlaxoSmithKline Services Unlimited
is 980 Great West Road, Brentford, Middlesex TW8 9GS.

Received on Tue Jul 30 2019 - 08:52:45 EDT

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