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RE: [NMusers] Using evid 0 before dosing

From: <>
Date: Wed, 6 Nov 2019 15:25:03 +0000

Dear Carlos,
You could also use an EVID=2 to do a read-out of a certain compartment.

-----Oorspronkelijk bericht-----
Van: <> Namens Bill Denney
Verzonden: woensdag 6 november 2019 16:12
Aan: Carlos ST <>;
Onderwerp: RE: [NMusers] Using evid 0 before dosing

Hi Carlos,

It is commonly used. For most datasets, there will be at least one observation that occurs before dosing to estimate the baseline value, and in almost every scenario, the modeling dataset should mirror the real world actions. So, there is no issue with it, and usually you will have an EVID=0 before the first dose.



-----Original Message-----
From: <> On Behalf Of Carlos ST
Sent: Wednesday, November 6, 2019 10:03 AM
Subject: [NMusers] Using evid 0 before dosing

Dear NMUsers,

I would like advice in the best practice to use evid 0 before dosing, which is to say an observation just before a dosing (*to estimate the value in that compartment just before dosing event).

Thank you,


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Received on Wed Nov 06 2019 - 10:25:03 EST

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