NONMEM Users Network Archive

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[NMusers] Upcoming webinar: Hybrid Genetic Algorithm Approaches to Model Selection

From: Rebecca Baillie <rbaillie_at_rosaandco.com>
Date: Thu, 17 Oct 2019 17:42:47 +0000

Hybrid Genetic Algorithm Approaches to Model Selection

Speaker: Robert Bies, Pharm.D. Ph.D
 Associate Professor of Pharmaceutical Sciences,
Member Computational and Data Enabled Sciences Program
University at Buffalo, NY

Thursday, Oct 24, 2019, 12:00 to 1:00 pm EDT

Register for free at https://www.rosaandco.com/webinars

Abstract:
A newly implemented version of an established Genetic Algorithm based appro=
ach using NONMEM with some modifications into an R-shiny package that provi=
des the same functionality with additional flexibility is presented.

Some refinements have been made in the selection process for evaluating mod=
els compared with the original evolutionary algorithm. Several population a=
nalyses using the updated algorithm are compared with results obtained usin=
g classical stepwise approaches in xenograft tumor growth profiles and popu=
lation pharmacokinetic analyses



Received on Thu Oct 17 2019 - 13:42:47 EDT

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